GO
 
Publications

NFGC - Supported Publications from 2005

  1. Park J, Brena RM, Gruidl M, Zhou J, Huang T, Plass C, Tockman MS. CpG island hypermethylation profiling of lung cancer using restriction landmark genomic scanning (RLGS) analysis. Cancer Biomark. 2005; 1(2-3):193-200. PMID: 17192040 (Tissue Procurement Core).

  2. Kamath SG, Chen N, Enkemann SA, Sanchez-Ramos J. Transcriptional profile of NeuroD expression in a human fetal astroglial cell line. Gene Expr. 2005; 12(2):123-36. PMID: 15892453 (Microarray Core).

  3. Takada N, Yamaguchi H, Shida K, Terajima D, Satou Y, Kasuya A, Satoh N, Satake M, Wang HG. The cell death machinery controlled by Bax and Bcl-XL is evolutionarily conserved in Ciona intestinalis. Apoptosis. 2005 Dec; 10(6):1211-20. PMID: 16215691 (Drug Discovery Core and Analytic Microscopy Core).

  4. Marchion DC, Bicaku E, Daud AI, Sullivan DM, and Munster PN. In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates. Mol Cancer Ther. 2005 Dec; 4 (12):1993-2000. PMID: 16373714 (Munster Pilot Project).

  5. Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S, Niu G, Kay H, Mule J, Kerr WG, Jove R, Pardoll D, Yu H. Inhibiting Stat3 signaling in the hematopoietic system elicits multi-component antitumor immunity. Nat Med. 2005 Dec; 11(12):1314-21. Epub 2005 Nov 20. PMID: 16288283

  6. Guida WC, Hamilton AD, Crotty JW, Sebti SM. Protein farnesyltransferase: Flexible docking studies on inhibitors using computational modeling. J Comput Aided Mol Des. 2005 Dec; 19(12):871-85. Epub 2006 May 12. PMID: 16607571 (High Throughput Screening Core).

  7. Arora R, Kundel HL, Beam CA. Perceptually Based FROC Analysis (1). Acad Radiol. 2005 Dec; 12(12):1567-74. PMID: 16321746 (Biostatistics Core).

  8. Marchion DC, Bicaku E, Turner JG, Daud AI, Sullivan DM, and Munster PN.  Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta. Clin Cancer Res. 2005 Dec 1; 11(23):8467-75. PMID: 16322310 (Munster Pilot Project).

  9. Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu J, Sebti SM, Youle RJ, Wang HG. Loss of bif-1 suppresses bax/bak conformational change and mitochondrial apoptosis. Mol Cell Biol. 2005 Nov; 25(21):9369-82. PMID: 16227588 (Drug Discovery Core and Analytic Microscopy Core).

  10. Chu F, Koomen JM, Kobayashi R, O’Brian CA. Identification of inactivating cysteine switch in protein kinase Cepsilon, a rational target for the design of protein kinase Cepsilon-inhibitory cancer therapeutics. Cancer Res. 2005 Nov 15; 65(22): 10478-85. PMID: 16288040 (Proteomics Core).

  11. Nefedova Y, Nagaraj S, Rosenbauer A, Muro-Cacho C, Sebti SM, Gabrilovich DI. Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway. Cancer Res. 2005 Oct 15; 65(20):9525-35. PMID: 16230418 (Drug Discovery Core).

  12. Nam S, Kim D, Cheng JQ, Zhang S, Lee JH, Buettner R, Mirosevich J, Lee FY, Jove R. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res. 2005 Oct 15; 65(20):9185-9. PMID: 16230377

  13. Nefedova Y, Cheng P, Gilkes D, Blaskovich M, Beg A, Sebti S, Gabrilovich DI. Activation of Dendritic Cells via Inhibition of Jak2/STAT3 Signaling. J Immunol. 2005 Oct 1; 175(7):4338-46. PMID: 16177074 (Analytic Microscopy Core).

  14. Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Role of Stat3 in regulating p53 expression and function. Mol Cell Biol. 2005 Sep; 25(17):7432-40. PMID: 16107692 (Analytic Microscopy Core).

  15. Mohapatra S, Chu B, Zhao X, Pledger WJ. Accumulation of p53 and reductions in XIAP abundance promote the apoptosis of prostate cancer cells. Cancer Res. 2005 Sep 1; 65(17):7717-23. PMID: 16140939

  16. Bali P, Pranpat M, Swaby R, Fiskus W, Yamaguchi H, Balasis M, Rocha K, Wang HG, Richon V, Bhalla K.  Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2. Clin Cancer Res. 2005 Sep 1; 11(17):6382-9. PMID: 16144943 (Analytic Microscopy Core).

  17. Kwong KY, Bloom GC, Yang I, Boulware D, Coppola D, Haseman J, Chen E, McGrath A, Makusky AJ, Taylor J, Steiner S, Zhou J, Yeatman TJ, Quackenbush J. Synchronous global assessment of gene and protein expression in colorectal cancer progression. Genomics. 2005 Aug; 86(2):142-58. PMID: 15951154 (Biostatistics Core and Yeatman Colon Cancer Project).

  18. Cook AC, Tuck AB, McCarthy S, Turner JG, Irby RB, Bloom GC, Yeatman TJ, Chambers AF. Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression. Mol Carcinog. 2005 Aug; 43(4):225-36. PMID: 15864800 (Biostatistics Core).

  19. Xu Q, Briggs J, Park S, Niu G, Kortylewski M, Zhang S, Gritsko T, Turkson J, Kay H, Semenza GL, Cheng JQ, Jove R, Yu H. Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene. 2005 Aug 25; 24(36):5552-60. PMID: 16007214

  20. Torres-Roca JF, Eschrich S, Zhao H, Bloom G, Sung J, McCarthy S, Cantor AB, Scuto A, Li C, Zhang S, Jove R, Yeatman T. Prediction of radiation sensitivity using a gene expression classifier. Cancer Res. 2005 Aug 15; 65(16):7169-76. PMID: 16103067 (Biostatistics Core). 

  21. Buzzeo R, Enkemann S, Nimmanapalli R, Alsina M, Lichtenheld MG, Dalton WS, Beaupre DM. Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341. Clin Cancer Res. 2005 Aug 15; 11(16):6057-64. PMID: 16115951 (Microarray Core).

  22. Zhang X, Li P, Bao J, Nicosia SV, Wang H, Enkemann SA, Bai W. Suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin D3 revealed by microarray analysis. J Biol Chem. 2005 Aug 10. PMID: 16093247 (Microarray Core).

  23. Chen Q, Van der Sluis PC, Boulware D, Hazlehurst LA, Dalton WS. The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells. Blood. 2005 Jul 15; 106(2):698-705. Epub 2005 Mar 31. PMID: 15802532 (Biostatistics Core and Analytic Microscopy Core).

  24. Park JY, Chen L, Lee J, Sellers T, Tockman MS. Polymorphisms in the promoter region of neutrophil elastase gene and lung cancer risk. Lung Cancer. 2005 Jun; 48(3):315-21. PMID: 15892999

  25. Park JY, Chen L, Elahi A, Lazarus P, Tockman MS. Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk. Eur J Cancer Prev. 2005 Jun; 14(3):223-30. PMID: 15901990

  26. Haura EB, Turkson J, Jove R. Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer. Nat Clin Pract Oncol. 2005 Jun; 2(6):315-24. PMID: 16264989

  27. Zhu K, Gerbino E, Beaupre DM, Mackley PA, Muro-Cacho C, Beam C, Hamilton AD, Lichtenheld MG, Kerr WG, Dalton W, Alsina M, Sebti SM.  Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood. 2005 Jun 15; 105(12):4759-66. Epub 2005 Feb 22. PMID: 15728126 (Analytic Microscopy Core and Biostatistics Core).

  28. Eschrich S, Yang I, Bloom G, Kwong KY, Boulware D, Cantor A, Coppola D, Kruhoffer M, Aaltonen L, Orntoft TF, Quackenbush J, Yeatman TJ.  Molecular staging for survival prediction of colorectal cancer patients. J Clin Oncol. 2005 May 20; 23(15):3526-35. PMID: 15908663 (Biostatistics Core and Yeatman Colon Cancer Project).

  29. Berchuck A, Iversen ES, Lancaster JM, Pittman J, Luo J, Lee P, Murphy S, Dressman HK, Febbo PG, West M, Nevins JR, Marks JR.  Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. Clin Cancer Res. 2005 May 15; 11(10):3686-96. PMID: 15897565 (Lancaster Pilot Project).

  30. Dauer DJ, Ferraro B, Song L, Yu B, Mora L, Buettner R, Enkemann S, Jove R, Haura EB. Stat3 Regulates genes common to both wound healing and cancer. Oncogene. 2005 May 12; 24(21):3397-408. PMID: 15735721 (Haura Pilot Project).

  31. Marchion DC, Bicaku E, Daud AI, Sullivan DM, MunsterPN. Valproic Acid Alters Chromatin Structure by Regulation of Chromatin Modulation Proteins. Cancer Research. 2005 May 1; 65(9):3815-22. PMID: 15867379 (Munster Pilot Project, Analytic Microscopy Core).

  32. Berchuck A, Iverson ES, Lancaster JM, Dressman HK, West M, Nevins JR, Marks JR. Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays. Am J Obstst Gynecol. 2004 Apr; 190(4):910-25. PMID: 15118612 (Lancaster Pilot Project).

  33. Centeno B, Enkemann S, Coppola D, Huntsman S, Bloom G, Yeatman T. Classification of human tumors using gene expression profiles obtained after microarray analysis of fine-needle aspiration biopsy samples. Cancer. 2005 April 25; 105(2)101-109. PMID: 15643601 (Biostatistics Core and Microarray Core).

  34. Daud A, Valkov N, Centeno B, Derderian J, Sullivan P, Munster P, Urbas P, Deconti R, Berghorn E, Liu Z, Hausheer F, Sullivan D.  Phase II trial of karenitecin in patients with malignant melanoma: clinical and translational study. Clin Cancer Res. 2005 Apr 15; 11(8):3009-16. PMID: 15837755 (Analytic Microscopy Core).

  35. Kusmartsev S, Gabrilovich D. STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J Immunol. 2005 Apr 15; 174(8):4880-91. PMID: 15814715 (Analytic Microscopy Core).

  36. Wang C, Hou X, Mohapatra S, Ma Y, Cress WD, Pledger WJ, Chen J. Activation of p27Kip1 Expression by E2F1. A negative feedback mechanism. J Biol Chem. 2005 Apr 1; 280(13):12339-43. Epub 2005 Feb 14. PMID: 1571366

  37. Helm J, Enkemann SA, Coppola D, Barthel JS, Kelley ST, Yeatman TJ. Dedifferentiation precedes invasion in the progression from Barrett's metaplasia to esophageal adenocarcinoma. Clin Cancer Res. 2005 Apr 1; 11(7): 2478-85. PMID: 15814623 (Microarray Core).

  38. Park JY, Chen L, Wadhwa N, Tockman MS. Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD. Int J Mol Med. 2005 Mar; 15(3):443-8. PMID: 15702235

  39. Joshi B, Ordonez-Ercan D, Dasgupta P, Chellappan S. Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors. Oncogene. 2005 Mar 24; 24(13):2204-17. PMID: 15735762 (Analytic Microscopy Core, Microarray Core and Molecular Biology Core).

  40. Ferraro B, Bepler G, Sharma S, Cantor A, Haura E. EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer. J Clin Oncol. 2005 March 20; 23(9)1921-1926. PMID: 15774784 (Molecular Biology and Analytic Microscopy Cores).

  41. Sung J, Turner J, McCarthy S, Enkemann S, Li CG, Yan P, Huang T, Yeatman TJ. Oncogene regulation of tumor suppressor genes in tumorigenesis. Carcinogenesis. 2005 Feb; 26(2):487-94. Epub 2004 Oct 21. PMID: 15498783 (Microarray Core).

  42. Harbig J, Sprinkle R, Enkemann SA. A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array. Nucleic Acids Res. 2005 Feb 18; 33(3):e31. PMID: 15722477 (Biostatistics Core and Microarray Core).

  43. George P, Bali P, Annavarapu S, Scuto A, Fiskus W, Guo F, Sigua C, Sondarva G, Moscinski L, Atadja P, Bhalla K. Combination of histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3. Blood. 2005 Feb 15; 105(4):1768-76. Epub 2004 Oct 28. PMID: 15514006 (Bhalla Pilot Project, Analytic Microscopy Core).

  44. Guo F, Sigua C, Bali P, George P, Fiskus W, Scuto A, Annavarapu S, Mouttaki A, Sondarva G, Wei S, Wu J, Djeu J, Bhalla K.  Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells. Blood. 2005 Feb 1; 105(3):1246-55. Epub 2004 Sep 23. PMID: 15388581 (Bhalla Pilot Project, Analytic Microscopy Core).

  45. Dobbin KK, Beer DG, Meyerson M, Yeatman TJ, Gerald WL, Jacobson JW, Conley B, Buetow KH, Heiskanen M, Simon RM, Minna JD, Girard L, Misek DE, Taylor JM, Hanash S, Naoki K, Hayes DN, Ladd-Acosta C, Enkemann SA, Viale A, Giordano TJ. Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1): 565-72. PMID: 15701842 (Microarray Core).

Page edited 9/16/09
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